TURN DOWN TEXUTRES, Even though it said I could run with Very High Textures and it was within my VRAM limit, when I turned the textures down to High it stopped my micro sutters/hitching.!! (I think this is the most important thing that affected my experience so far)
Turn off raytracing. Have v-sync off in game and force it through nvidia control panel (or whatever the amd equivalent is) I have seen reports that above 60 fps causes mouse input issues, but for me I have been playing around 100 fps for a couple of hours and had no issue
TL;DR Turn down textures and turn off ray tracing.